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Updated: Dec 10, 2025

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
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Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

Published on: April 9, 2018

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タンデム・バイオオートホグナル・ラベリングにより,内在的なコトランスレーションによるO-GlcNAc変異した新生タンパク質が発見された

Yanping Zhu1,2, Lianne I Willems1, Daniela Salas1,3

  • 1Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.

Journal of the American Chemical Society
|September 2, 2020
PubMed
まとめ

この研究では,O-GlcNAcによって翻訳中に変化した内生タンパク質を特定し,タンパク質の恒常性のための新しいメカニズムを明らかにしました. これらの発見は,O-GlcNAcの理解を深める.

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