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Updated: Dec 9, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

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協力的な計算と実験的探査を通じて多形リスクを最小限に抑える

Christopher R Taylor1, Matthew T Mulvee2, Domonkos S Perenyi2

  • 1Computational Systems Chemistry, School of Chemistry, University of Southampton, Southampton SO17 1NX, U.K.

Journal of the American Chemical Society
|September 8, 2020
PubMed
まとめ

コンピューターによる結晶構造予測 (CSP) と実験を組み合わせて,アイソニアジドとイプロニアジドの難解なポリモルフを成功裏に特定し,医薬品の固体形態に関連するリスクを最小限に抑えました.

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