関連する実験動画

Updated: Dec 9, 2025

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
22:10

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Published on: June 28, 2013

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インフルエンザAウイルスの組み立てられたマトリックスタンパク質1の原生構造

Julia Peukes1,2,3, Xiaoli Xiong4,5, Simon Erlendsson1

  • 1Structural Studies Division, Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.

Nature
|September 10, 2020
PubMed
まとめ

マトリックスタンパク質1 (M1) は,インフルエンザウイルスの組み立てに不可欠な線形鎖を形成します. この構造は,M1のポリメリゼーションを明らかにし,細胞に入ってからウイルスの解体のためのpH感受性スイッチとして機能します.

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Leaky Scanning02:28

Leaky Scanning

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
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