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Updated: Dec 9, 2025

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
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Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Published on: September 13, 2013

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遺伝子でコードされたキノンメソッド,アミン反応剤による迅速な,サイト特異的な,そして光制御されたタンパク質改変を可能にする

Jun Liu1, Rujin Cheng2, Ned Van Eps3

  • 1Department of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California San Francisco, 555 Mission Bay Blvd. South, San Francisco, California 94158, United States.

Journal of the American Chemical Society
|September 11, 2020
PubMed
まとめ

研究者は,遺伝子組み換えアミノ酸を用いたサイト固有のタンパク質改変のための新しいフォトケージング方法を開発しました. この技術は,光制御可能なキノンメチド (QM) による機能分子による精密なタンパク質ラベルを可能にします.

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