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Updated: Dec 8, 2025

Co-immunoprecipitation of the Mouse Mx1 Protein with the Influenza A Virus Nucleoprotein
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Co-immunoprecipitation of the Mouse Mx1 Protein with the Influenza A Virus Nucleoprotein

Published on: April 21, 2015

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インフルエンザA M2阻害剤の結合は,過剰プロトン安定化とチャネルダイナミクスのメカニズムによって理解される

Laura C Watkins1, William F DeGrado2, Gregory A Voth1

  • 1Department of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics and James Franck Institute, The University of Chicago, Chicago, Illinois 60637, United States.

Journal of the American Chemical Society
|September 16, 2020
PubMed
まとめ

新しい研究は,インフルエンザAのM2チャネル阻害剤が,陽子輸送を模倣してどのように作用するかを明らかにしています. このメカニズムに基づく抑制は 耐性菌株に対する より効果的な抗ウイルス薬の設計に 重要な洞察をもたらします

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