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Updated: Dec 8, 2025

Do's and Don'ts of Cryo-electron Microscopy: A Primer on Sample Preparation and High Quality Data Collection for Macromolecular 3D Reconstruction
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Do's and Don'ts of Cryo-electron Microscopy: A Primer on Sample Preparation and High Quality Data Collection for Macromolecular 3D Reconstruction

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トランジション状態の90S小リボソームサブユニット前駆体による冷凍-EM構造

Yifei Du1, Weidong An1, Xing Zhu1

  • 1Key Laboratory of RNA Biology, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Science (New York, N.Y.)
|September 18, 2020
PubMed
まとめ

90Sプレリボソーム内の切断された5'外部転写されたスペーサー (5' ETS) RNAの分解は,小さなリボソームサブユニットの成熟を誘導する. このプロセスは核エクソソームとヘリコースMtr4を巻き込み,リボソームの生体生成を促進する.

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