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Updated: Dec 8, 2025

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
07:30

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice

Published on: July 9, 2016

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ハルシノゲン活性化Gq結合5-HT2Aセロトニン受容体の構造

Kuglae Kim1, Tao Che1, Ouliana Panova2

  • 1Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599-7365, USA.

Cell
|September 18, 2020
PubMed
まとめ

LSDやサイロシビンのような幻覚剤がセロトニン5HT2A受容体 (HTR2A) を活性化させる仕組みの構造的な洞察が明らかになった. これらの分子メカニズムを理解することは 神経精神疾患の新たな治療法の開発の鍵です

キーワード:
GPCR についてLSD についてサイケデリックセロトニン受容体信号変換構造生物学

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