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Updated: Dec 5, 2025

Characterizing Mutational Load and Clonal Composition of Human Blood
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97,691の全ゲノムにおけるクローン性血液形成の遺伝的原因

Alexander G Bick1,2,3,4, Joshua S Weinstock5, Satish K Nandakumar2,6

  • 1Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.

Nature
|October 15, 2020
PubMed
まとめ

老化により慢性疾患のリスクが増加します この研究では,がんや心臓病に関連した状態であるクローン性血液形成 (CHIP) に影響する遺伝的要因を特定し,生殖系統の変異が幹細胞機能にどのように影響するかを明らかにしました.

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