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ニューロピリン-1はSARS-CoV-2感染の宿主因である

James L Daly1, Boris Simonetti2, Katja Klein3

  • 1School of Biochemistry, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.

Science (New York, N.Y.)
|October 21, 2020
PubMed
まとめ

SARS-CoV-2のスパイクタンパク質は,CendRモチーフを介して宿主細胞受容体に結合する. このニューロピリン-1 (NRP1) との相互作用は,ウイルスの侵入に不可欠であり,COVID-19の潜在的な治療標的としてNRP1を示唆しています.

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