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Updated: Dec 4, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Published on: September 20, 2018

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エピジェネティック療法により,逆転SINEとADAR1依存性の転写が誘発される

Parinaz Mehdipour1, Sajid A Marhon2, Ilias Ettayebi2,3

  • 1Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. parinaz.mehdipour@uhnresearch.ca.

Nature
|October 22, 2020
PubMed
まとめ

エピジェネティック療法では,二重鎖RNA (dsRNA) を介して,がん細胞を殺すレトロエレメントを活性化します. これらの治療法とADAR1阻害剤を併用すると,ウイルスのミミクリ反応を刺激することで,がん治療が改善されます.

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