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Updated: Dec 4, 2025

Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
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Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons

Published on: August 6, 2014

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RNAの時間解像度,単分子,相関化学探査

Jeffrey E Ehrhardt1, Kevin M Weeks1

  • 1Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, United States.

Journal of the American Chemical Society
|October 23, 2020
PubMed
まとめ

新しい化学探査機であるトリメチロキソニウム (TMO) は,RNAの折り畳みダイナミクスを直接,時間分解で測定することができます. この方法は,RNase P RNAの長距離相互作用によって導かれる非階層的な折り畳みメカニズムを明らかにした.

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