ゲノミクスの最前線で人間の健康を改善するための戦略的ビジョン

Eric D Green¹, Chris Gunter², Leslie G Biesecker²

¹National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. egreen@nhgri.nih.gov.

Nature

|October 29, 2020

まとめ

ヒトゲノムプロジェクトによって開始されたゲノミクス研究は,基礎的,翻訳的,臨床的研究においてますます重要になっています. 医療や公衆衛生に広く統合され日常生活にも影響を与えるでしょう

科学分野:

ゲノミクスと人間の健康
バイオメディカル研究
ゲノム医学

背景:

ヒューマンゲノムプロジェクト (HGP) は,その開始以来,研究におけるゲノミクスの中心的な役割を果たしました.
ゲノム情報は効果的な臨床治療の応用としてますます有効化されています
ゲノミクスは研究から主流の医療や公衆衛生に移行しています

研究の目的:

ヒトゲノム学における将来の研究優先事項と機会を概説する.
ゲノミクスの最前線で重要な進歩を特定し,健康への応用に焦点を当てます.
ゲノム研究と医療への統合の次の段階を導くこと

主な方法:

研究コミュニティとの多年にわたる戦略的関与プロセス
将来のヒトゲノム研究の最優先要素を特定する.
最先端の技術と臨床応用に焦点を当てる

主要な成果:

ゲノミクスは基礎的および翻訳的研究において触媒的な役割を果たします
ゲノム情報によると臨床治療の有効性が向上しています
予想される進歩は,生物医学研究と公衆衛生へのより広範な統合を推進します.

結論:

ゲノミクスは生物医学研究と医療におけるより広範な統合に備わっています
将来のゲノム解析の進歩は医療や公衆衛生の改善につながるでしょう
ゲノミクスは日常生活と個人の健康管理にますます重要になります

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