皮膚性メラノーマの危険因子 傾向のある個人を認識するための実用的な方法
A R Rhodes1, M A Weinstock, T B Fitzpatrick
1Department of Dermatology, Massachusetts General Hospital, Boston 02114.
JAMA
|December 4, 1987
まとめ
皮膚性メラノーマの早期発見は,治療の成功の鍵です. 変異性モールやメラノーマの病歴などの危険因子を有する個人を特定することで,がんによる死亡率を大幅に減らすことができます.
科学分野:
- 皮膚科 皮膚科について
- 腫瘍学 腫瘍学
- がん研究 がん研究
背景:
- 皮膚性メラノーマは,公衆衛生上の重大な懸念事項である.
- 早期発見は,治療結果と治癒率を劇的に改善します.
- 多くの癌とは異なり,メラノーマは皮膚でよく見られ,早期発見が容易になります.
研究 の 目的:
- 皮膚性メラノーマの主要な危険因子を特定する.
- リスクの高い個人を選択的にスクリーニングするための戦略を参考にすること.
- メラノーマに関連した罹病率と死亡率を減らすために.
主な方法:
- 皮膚性メラノーマの既定および新興の危険因子のレビュー.
- 様々なリスク要因の相対的な重要性を分析する.
- 早期発見のための臨床検査に重点を置く.
主要な成果:
- 主要な危険因子には,持続的に変化したモール,成人期,不規則な色素の病変,先天性モール,白人の人種,既往のメラノーマ,家族歴,免疫抑制,太陽感受性,過剰な太陽曝露が含まれます.
- これらの要因は重要度順に並べられ,リスクのある集団を特定するのに役立ちます.
- 皮膚検査による早期発見は極めて重要です.
結論:
- 特定の危険因子を持つ個人を特定することは,標的型スクリーニングに不可欠です.
- メラノーマの積極的なスクリーニングと早期の治療は,死亡率を下げることができます.
- メラノーマの危険因子に対する公衆の認識は,個人および医療提供者に対して力を与えることができます.
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