オービトフロントアル皮質にコードされた値は 経済的選択と因果関係があります
Sébastien Ballesta1,2,3, Weikang Shi1, Katherine E Conen1,4
1Department of Neuroscience, Washington University in St Louis, St Louis, MO, USA.
Nature
|November 3, 2020
まとめ
科学者は猿の電気刺激を用いて 軌道前皮質 (OFC) の脳活動が主観的な価値計算を変えることで 経済的な選択に影響を及ぼすことを証明しました
科学分野:
- 神経科学
- 神経経済学
- 意思決定科学
背景:
- 経済的選択は,主観的な価値計算と歴史的に結びついています (ベルヌーリ,スミス,ベンサム).
- 意思決定の過程で主観的な価値をコードします
- 脳の活動と経済的な選択を 結びつける以前の証拠は 相関関係でした
研究 の 目的:
- OFCにおけるニューロンの活動と経済的な選択の間の因果関係を確立する.
- 主観的な値の計算と比較における OFC の役割を調査する.
主な方法:
- レサス猿のOFCの電気刺激に関する2つの実験
- 低電流と高電流の刺激で ニューロンの活動を操作する
- 主観的な価値認識と,その後の選択への影響を観察する.
主要な成果:
- 低電流刺激は主観的な価値を増やすことで 予測可能な偏った選択をします
- 高電流刺激は主観的な値の計算と比較を妨害し,選択の変動性を増加させた.
- OFCの活動と経済的な意思決定の間の因果関係を証明した.
結論:
- OFCにおけるニューロンの活動は 経済的な選択と因果関係があります
- OFCは,経済的な決定の基礎となる評価と選択の両方で重要な役割を果たします.
- 経済的行動における主観的な価値の 神経的基礎の直接的な証拠を提供する.
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