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Updated: Dec 2, 2025

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters
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プロトン活性化塩素チャネルの構造とpH感知機構

Zheng Ruan1, James Osei-Owusu2, Juan Du1

  • 1Department of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA.

Nature
|November 5, 2020
PubMed
まとめ

陽子活性化塩化物チャネル (PAC) は,酸による細胞損傷において極めて重要です. 新しい構造は,pHの変化がPACの閉塞を引き起こし,その活性化メカニズムの洞察を提供します.

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