Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

4.5K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
4.5K
From DNA to Protein03:06

From DNA to Protein

21.2K
The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
21.2K
The Central Dogma01:20

The Central Dogma

31.1K
The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
31.1K
The Central Dogma01:25

The Central Dogma

136.6K
Overview
136.6K
Gene Conversion02:08

Gene Conversion

10.3K
Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
10.3K
Gene Conversion02:08

Gene Conversion

2.7K
2.7K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Visionary AI: Decoding Systemic Vascular Health and Hypertensive Disorders in Pregnancy Through Retinal Imaging and Artificial Intelligence.

medRxiv : the preprint server for health sciences·2025
Same author

Megaplasmids associate with <i>Escherichia coli</i> and other <i>Enterobacteriaceae</i>.

bioRxiv : the preprint server for biology·2025
Same author

CaDAVEr: a metagenome-assembled genome catalog of microbial decomposers across vertebrate environments.

Microbiology resource announcements·2025
Same author

Competitive fungal commensalism mitigates candidiasis pathology.

The Journal of experimental medicine·2024
Same author

Contamination source modeling with SCRuB improves cancer phenotype prediction from microbiome data.

Nature biotechnology·2023
Same author

STENSL: Microbial Source Tracking with ENvironment SeLection.

mSystems·2022
Same journal

A native sulfur deposit in Gale crater, Mars.

Science (New York, N.Y.)·2026
Same journal

Coordinated demise of harmful algal blooms.

Science (New York, N.Y.)·2026
Same journal

Genetic effects put into context.

Science (New York, N.Y.)·2026
Same journal

Bacteria share proteins to survive antibiotics.

Science (New York, N.Y.)·2026
Same journal

Impacts shaped Earth's first continents.

Science (New York, N.Y.)·2026
Same journal

Erratum for the Report "Covalently bonded single-molecule junctions with stable and reversible photoswitched conductivity" by C. Jia <i>et al</i>.

Science (New York, N.Y.)·2026
関連記事をすべて見る

関連する実験動画

Updated: Dec 2, 2025

Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System
11:47

Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System

Published on: August 1, 2016

16.2K

資源の保存は遺伝子コードに表れています

Liat Shenhav1,2, David Zeevi3

  • 1Center for Studies in Physics and Biology, Rockefeller University, New York, NY, USA.

Science (New York, N.Y.)
|November 6, 2020
PubMed
まとめ
この要約は機械生成です。

栄養素の微生物の競争が 遺伝子コードを形作ります この資源の保存は窒素の利用により ヒトを含む生命体全体に 変異の保護をもたらします

さらに関連する動画

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers
10:41

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers

Published on: June 24, 2019

8.7K
Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans
09:23

Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans

Published on: August 16, 2017

8.4K

関連する実験動画

Last Updated: Dec 2, 2025

Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System
11:47

Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System

Published on: August 1, 2016

16.2K
Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers
10:41

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers

Published on: June 24, 2019

8.7K
Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans
09:23

Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans

Published on: August 16, 2017

8.4K

科学分野:

  • 微生物生態学
  • 分子 進化
  • バイオ情報学

背景:

  • 栄養素の制限は 生物間の競争の主要な原動力です
  • 微生物のコード配列に対する栄養素の利用可能性の影響は,まだほとんど研究されていない.
  • 遺伝子配列に対する選択的圧力を理解することは 進化生物学にとって極めて重要です

研究 の 目的:

  • 微生物のコード配列の進化に 栄養素の制限がどう影響するかを調べる
  • 遺伝的選択の形成における環境要因,特に窒素の利用可能性の役割を特定する.
  • 遺伝子コードの構造が 資源によって引き起こされる変異に対して 頑丈性があるかどうかを判断する

主な方法:

  • 海洋微生物からのメタゲノミクスと単細胞データの分析
  • 環境測定を統合し,栄養素の利用可能性に焦点を当てます.
  • 標準的な遺伝子コードの構造とコドン使用パターンの検討

主要な成果:

  • 微生物のゲノムにおける 選択の大部分は 環境に左右され 窒素の利用可能性と関連しています
  • 遺伝子コードは タンパク質の炭素と窒素の含有量を高める 変異に対して固有の強度を示しています
  • この保護メカニズムは 微生物からヒトゲノムまで 様々な分類に保たれています

結論:

  • 資源主導の選択は,特に窒素に関して,微生物のゲノム進化に大きく影響します.
  • 標準的な遺伝子コードのデザインは本質的に 重要な要素を保ちながら 変異の強さをもたらします
  • これらの発見は 環境の栄養レベルと 生命のあらゆる領域における 遺伝子の進化的最適化との 根本的な関係を明らかにしています