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Updated: Nov 29, 2025

Examining BCL-2 Family Function with Large Unilamellar Vesicles
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小分子誘発ポリメリゼーションはBCL6の分解を誘発する

Mikołaj Słabicki1,2,3, Hojong Yoon4,5, Jonas Koeppel1,2,3

  • 1Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Nature
|November 19, 2020
PubMed
まとめ

新しい小分子BI-3802は,腫瘍性転写因子B細胞リンパ腫6 (BCL6) をポリメリ化し,細胞集積を形成させ,タンパク質分解を誘導する.

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