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Updated: Nov 29, 2025

A New Screening Method for the Directed Evolution of Thermostable Bacteriolytic Enzymes
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A New Screening Method for the Directed Evolution of Thermostable Bacteriolytic Enzymes

Published on: November 7, 2012

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誘導的進化が酵素のエネルギー環境を変化させ,触媒を活性化させる方法

Renee Otten1, Ricardo A P Pádua1, H Adrian Bunzel2

  • 1Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University, Waltham, MA 02454, USA.

Science (New York, N.Y.)
|November 20, 2020
PubMed
まとめ

誘導進化は 計算で設計された酵素を プロトンの移転に最適化し 触媒速度を劇的に増加させました この 過程 で,タンパク質 の 骨組み が 精製 さ れ まし た

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