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Updated: Nov 28, 2025

Analysis of Termination of Transcription Using BrUTP-strand-specific Transcription Run-on TRO Approach
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Analysis of Termination of Transcription Using BrUTP-strand-specific Transcription Run-on TRO Approach

Published on: March 12, 2017

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トランスロケーション独立RNAポリメラーゼをターミネーターATPアゼで無活性化するためのステップ

Nelly Said1, Tarek Hilal2, Nicholas D Sunday3

  • 1Laboratory of Structural Biochemistry, Institute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.

Science (New York, N.Y.)
|November 27, 2020
PubMed
まとめ

タンパク質複合体であるRho (ρ) 因子はRNAポリメラーゼを捕まえて遺伝子転写を終了させます. Cryo-EM構造は,RhoがNusAとNusGタンパク質と相互作用してDNAを解き放ち,RNAを放出し,転写を停止する方法を明らかにします.

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