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ガイドRNA分類は,Tn7-CRISPR-Casトランポゾンにおける標的部位の選択を可能にします

Michael T Petassi1, Shan-Chi Hsieh1, Joseph E Peters1

  • 1Department of Microbiology, Cornell University, Ithaca, NY 14853, USA.

Cell
|December 3, 2020
PubMed
まとめ

Tn7のような元素のCRISPR-Casシステムは,トランポジションのために特殊なガイドRNAを使用します. これにより,移動性プラズミッドと染色体部位の両方を標的とし,効率的な遺伝子転送と宿主コロニー化を可能にします.

キーワード:
CRISPR規制についてRNA指向トランスポーゼーションガイドRNAの分類自動ターゲティングの距離計

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