結核薬ベダキリンに結合するミコバクテリアのATP合成の構造

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Updated: Nov 26, 2025

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
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Hui Guo1,2, Gautier M Courbon1,2, Stephanie A Bueler1

  • 1Molecular Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada.

Nature
|December 10, 2020
PubMed
まとめ

結核の治療には抗生物質耐性があります 新しい研究により,耐性結核の重要な薬であるベダキリンが,Mycobacterium tuberculosis ATP合成酵素に正確に結合し,眠っている細菌に対するその強力なメカニズムの新たな理解を可能にしました.

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