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関連する概念動画

Maxwell's Thermodynamic Relations01:23

Maxwell's Thermodynamic Relations

4.0K
Maxwell's thermodynamic relations are very useful in solving problems in thermodynamics. Each of Maxwell's relations relates a partial differential between quantities that can be hard to measure experimentally to a partial differential between quantities that can be easily measured. These relations are a set of equations derivable from the symmetry of the second derivatives and the thermodynamic potentials.
All thermodynamic potentials are exact differentials. Therefore, their second-order...
4.0K
Phase Transitions: Vaporization and Condensation02:39

Phase Transitions: Vaporization and Condensation

20.0K
The physical form of a substance changes on changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. Vaporization occurs when the thermal motion of the molecules overcome the intermolecular forces, and the molecules (at the surface) escape into the gaseous state. When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules...
20.0K
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.0K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.0K
Membrane Fluidity01:23

Membrane Fluidity

168.6K
Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.
168.6K
Membrane Fluidity01:26

Membrane Fluidity

13.8K
Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is...
13.8K
Characteristics of Fluids01:20

Characteristics of Fluids

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When a force is applied parallel to the top surface of a solid, it resists the applied force due to the internal frictional forces between the layers of the solid known as shearing resistance. However, when the force is removed, the shearing forces restore the original shape of the solid. Other deformation forces also cause temporary changes in shape if the forces are not beyond a threshold magnitude. Solids tend to retain their shape, making the study of their rest and motion easier. Beyond...
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Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures
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マクスウェル流体として老化するタンパク質凝縮物

Louise Jawerth1,2, Elisabeth Fischer-Friedrich3,4, Suropriya Saha1

  • 1Max Planck Institute for the Physics of Complex Systems, Nöthnitzer Str. 38, 01187 Dresden, Germany.

Science (New York, N.Y.)
|December 11, 2020
PubMed
まとめ
この要約は機械生成です。

タンパク質凝縮物はマクスウェルのガラスのように作用し,時間に依存する粘弾性特性を表します. 年齢とともに粘度が増加し 細胞生化学の調節に洞察を与えます

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Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
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Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
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Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells
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科学分野:

  • バイオ物理学
  • 柔らかい物質の物理
  • 細胞生物学

背景:

  • タンパク質凝縮物は,ダイナミックな物質特性を有する複雑な流体です.
  • これらの液体の包括的なレオロジカルな記述は,現在欠けている.

研究 の 目的:

  • インビトロタンパク質凝縮物の時間に依存するレオロジック特性を特徴付ける.
  • タンパク質コンデンサートの適切なレオロギーモデルを確立する.

主な方法:

  • レーザーピンチベースのアクティブレオロギーを使った.
  • マイクロビーズベースの受動的なレオロギーを特徴に用いる.
  • 電子顕微鏡を用いて構造変化を分析した.

主要な成果:

  • タンパク質の凝縮物は,異なる年齢で粘着弾性マクスウェル流体の振る舞いを表しています.
  • 凝縮液の老化に伴い,粘度が著しく増加する.
  • 弾性モジュールは年齢によって最小の変動を示し,有意な構造的変化は見られませんでした.

結論:

  • タンパク質の凝縮物は 柔らかいガラス状の材料として機能し マクスウェルのガラスと呼ばれています
  • これらの材料は細胞生化学の調節に不可欠な年齢に依存する性質を持っています.