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Updated: May 8, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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前編成型サイクロペプチド阻害剤によるAF9 YEATS領域の選択的標的化

Yixiang Jiang1, Guochao Chen2,3, Xiao-Meng Li1

  • 1Departments of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

Journal of the American Chemical Society
|December 11, 2020
PubMed
まとめ

研究者は,AF9 YEATSドメインを選択的に標的とする新しいサイクロペプチド阻害剤,JYX-3を開発しました. この突破は,がんのような YEATS領域に関連した病気に対する薬の開発の有望な新しい道を提供します.

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Efficient and Site-specific Antibody Labeling by Strain-promoted Azide-alkyne Cycloaddition09:06

Efficient and Site-specific Antibody Labeling by Strain-promoted Azide-alkyne Cycloaddition

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Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope08:09

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope

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