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Updated: Nov 23, 2025

Identification of Kinase-substrate Pairs Using High Throughput Screening
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ペプチド基板の選択的阻害によってキナーゼ活性を制御する

Xiaowei Li, Tania M Palhano Zanela, Eric S Underbakke

    Journal of the American Chemical Society
    |January 4, 2021
    PubMed
    まとめ

    合成受容体はタンパク質のリン酸化を精密に制御し,これは重要な翻訳後の修正 (PTM) である. このブレークスルーにより,酸化部位を特定し,従来のキナーゼ抑制の限界を克服し,PTMを正確に操作することができます.

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