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Updated: Nov 22, 2025

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
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Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding

Published on: September 21, 2011

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グルココルチコイド結合結合受容体GPR97-Go複合体の構造

Yu-Qi Ping1,2,3, Chunyou Mao4,5, Peng Xiao3

  • 1CAS Key Laboratory of Receptor Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

Nature
|January 7, 2021
PubMed
まとめ

グルココルチコイドストレスホルモンは,アデションGタンパク質結合受容体G3 (ADGRG3) を活性化します. 構造研究は,これらのホルモンがADGRG3を結合し活性化する方法を明らかにし,GPCRの調節に関する洞察を提供します.

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Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization09:19

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