関連する実験動画

Updated: Nov 22, 2025

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

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自然単一ガイドRNAは,CRISPR-Cas発現を自己調節するためにCas9を再利用する

Rachael E Workman1, Teja Pammi1, Binh T K Nguyen1

  • 1Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|January 9, 2021
PubMed
まとめ

CRISPR-Casシステムは,独自のプロモーターを抑制する自然単一ガイドRNAによって制御され,ウイルス免疫と自己免疫毒性をバランスとします. この自己調節はタイプII-Aシステムで広く存在し,水平遺伝子転送を助長する.

キーワード:
CRISPR-Casについてカス9自己免疫性バクテリアの制御バクテリオファージスグRNAトラックルトラックRNA

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