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Updated: May 8, 2026

Light-sheet Fluorescence Microscopy to Capture 4-Dimensional Images of the Effects of Modulating Shear Stress on the Developing Zebrafish Heart
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Light-sheet Fluorescence Microscopy to Capture 4-Dimensional Images of the Effects of Modulating Shear Stress on the Developing Zebrafish Heart

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ループエクストルーションは,RAGスキャンのための生理的なIGHロクスの収縮を媒介する

Hai-Qiang Dai1,2, Hongli Hu3,4, Jiangman Lou3,4

  • 1Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. hai-qiang.dai@childrens.harvard.edu.

Nature
|January 14, 2021
PubMed
まとめ

祖先のB細胞におけるRAGスキャンを調査すると,V(D) J再結合とは独立して場所の収縮が起こることが明らかになる. このプロセスはコヘシン媒介のループ流出とCTCF結合要素によって制御され,DNAアクセシビリティに影響を与えます.

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