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Updated: Nov 21, 2025

Analysis of SCAP N-glycosylation and Trafficking in Human Cells
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Published on: November 8, 2016

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Insig-2 に結合したヒトのScapの構造は,その相互作用がステロールによってどのように調節されるかを示唆している

Renhong Yan1,2, Pingping Cao3, Wenqi Song3

  • 1Westlake Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou 310024, Zhejiang Province, China.

Science (New York, N.Y.)
|January 15, 2021
PubMed
まとめ

コレステロールバランスに不可欠なステロール調節要素結合タンパク質 (SREBP) 経路は,ScapとInsigタンパク質によって調節されます. この研究は,ScapとInsig-2への25HC結合がSREBP経路の活性を制御する方法を明らかにしています.

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