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Updated: Nov 21, 2025

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
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Published on: June 24, 2020

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胎児の健康を母親の炎症から守るためにはGPER1が必要である

Alfred T Harding1, Marisa A Goff2, Heather M Froggatt1

  • 1Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.

Science (New York, N.Y.)
|January 15, 2021
PubMed
まとめ

妊娠はI型インターフェロン (IFN) 信号伝達に対する保護メカニズムを含み,母親の感染中に胎児の損傷を防ぐ. エストロゲン受容体GPER1 (グアニンヌクレオチド結合タンパク質結合されたエストロゲン受容体1) は,この免疫調節の鍵です.

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