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Updated: Nov 20, 2025

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart
08:22

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart

Published on: April 15, 2020

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イソレブグランディン改変された心臓タンパク質は,心臓におけるCD4+T細胞の活性化を促し,心臓機能障害を促進する

Njabulo Ngwenyama1, Annet Kirabo2, Mark Aronovitz3

  • 1Department of Immunology, Tufts University, Boston, MA (N.N., F.V., F.C.-S., A.M.S., T.N., A.T., P.A.).

Circulation
|January 19, 2021
PubMed
まとめ

酸化ストレスがT細胞を活性化し 心臓機能不全を引き起こします これらのイソレブグランジン (IsoLG) 変異を阻害すると,T細胞受容体 (TCR) の活性化が妨げられ,心臓が保護されます.

キーワード:
心不全炎症イソレブグランディン酸化ストレス

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