仮想組み合わせライブラリをスクリーニングすることにより,ヘテロレプティックPd6L6コーディネーションケージの識別
Sylvain Sudan1, Ru-Jin Li1, Suzanne M Jansze1
1Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Journal of the American Chemical Society
|January 21, 2021
まとめ
研究者は複雑なパラジウム調整ケージを作成するための新しい選択方法を開発しました. このアプローチにより,新しい構造モチーフを示す2つの異なる二酸化リガンドを持つユニークな六核パラジウムケージが成功しました.
科学分野:
- 超分子化学
- 協調化学
- 材料科学
背景:
- 構造的に定義されたヘテロレプティック調整ケージの設計は複雑です.
- 現在,このようなケージの例はほとんど知られていない.
- パラジウム複合体は,超分子化学における多用途な構成要素です.
研究 の 目的:
- ヘテロレプティック・コーディネーション・ケージを特定するための新しい選択アプローチを開発する.
- 新しい六核パラジウムケージを 合成し特徴づけること
- パラジウムベースの調整アセンブリの構造的多様性を探求する.
主な方法:
- パラジアム-ディピリドール複合体の仮想組み合わせライブラリを作成.
- 先進技術を用いた反応混合物の分析
- 単結晶X線微分法による標的合成と構造解明.
主要な成果:
- 新しいヘテロレプティック六核パラディアムケージの識別, [Pd6L6L'6](BF4) 12.
- このケージは前例のない トライゴナル・アンチプリズマ構造を示しています
- 2つの異なる三角形のPd3L3マクロサイクルが6つのL'リガンドによって橋渡されている.
- メタロリガンドを用いてより大きな関連ケージを合成した.
結論:
- 開発された選択アプローチは,複雑な調整ケージを発見するのに有効です.
- 新しいパラジウムケージは 超分子化学における 重要な進歩を表しています
- この研究は複雑な分子構造を 設計する新しい道を開きます
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