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Updated: Nov 19, 2025

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
09:06

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice

Published on: February 20, 2019

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性別分化遺伝子制御ネットワークは,滑らかな筋肉細胞の現象変異に関与する動脈硬化症の女性キードライバー遺伝子を明らかにする

Robin J G Hartman1, Katie Owsiany2,3, Lijiang Ma4

  • 1Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, The Netherlands (R.J.G.H., M.M., H.M.d.R.).

Circulation
|January 27, 2021
PubMed
まとめ

冠動脈疾患 (CAD) の性差は女性における異なった遺伝子活動を含み,滑らかな筋肉細胞が重要な役割を果たします. 性別特有の経路を理解することは ターゲットを絞った治療法の開発に不可欠です

キーワード:
動脈硬化症遺伝子規制ネットワーク筋細胞,滑らかな筋肉セックスシステム生物学トランスクリプトーム

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In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
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