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Updated: May 7, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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CARD8はHIV-1プロテアース活性に対する炎症体センサーである

Qiankun Wang1, Hongbo Gao1, Kolin M Clark1

  • 1Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA.

Science (New York, N.Y.)
|February 5, 2021
PubMed
まとめ

CARD8炎症ゾームはHIV-1プロテアースの活動を検知する. この経路を活性化すると,感染した細胞の熱死を引き起こすことで,持続的なHIV-1感染を排除します.

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