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Updated: Nov 18, 2025

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
06:27

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells

Published on: May 6, 2013

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"TCR+/BCR+デュアル発現細胞とその関連する公共のBCRクローノタイプは1型糖尿病では濃縮されません"への回答

Rizwan Ahmed1, Zahra Omidian1, Adebola Giwa2

  • 1Department of Pathology, Johns Hopkins University School of Medicine, 720 Rutland Ave, Ross 664G, Baltimore, MD 21205, USA.

Cell
|February 5, 2021
PubMed
まとめ

1型糖尿病 (T1D) の患者におけるデュアルエクスプレッサー (DE) リンパ球は,特定のB細胞受容体 (BCR) クローンによって支配されています. このクローンはインスリン反応性T細胞を活性化する自己抗原をコードし,この発見は新しいデータ分析によって支持されています.

キーワード:
DE セルTCR についてX 細胞自己免疫性デュアルエキスプレッサー・セルインスリンミモトープ公的 BCR クロノタイプ1 型糖尿病xオートアンチゲン

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