慢性感染症の治療中のSARS-CoV-2の進化
Steven A Kemp1, Dami A Collier1,2,3, Rawlings P Datir2,3
1Division of Infection and Immunity, University College London, London, UK.
Nature
|February 5, 2021
まとめ
免疫抑制患者における慢性的なSARS-CoV-2感染は,ウイルスの進化と抗体耐性を引き起こした. 中和感度が低下したスパイクタンパク質の変種に適した回復期プラズマ療法.
科学分野:
- ウイルス学
- 免疫学
- ゲノミクス
背景:
- 重症急性呼吸器症候群コロナウイルス2 (SARS-CoV-2) のスパイクタンパク質は,ACE2受容体経由でウイルスの侵入を容易にし,抗体を中和する重要な標的である.
- 慢性感染症と治療的介入におけるウイルスの進化を理解することは,疾患の進行を管理する上で極めて重要です.
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