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Updated: Nov 18, 2025

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
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A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products

Published on: September 9, 2016

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塩基性窒素を含むα-またはβ-デオキシアミノグリコシドの合成の一般方法

Kevin M Hoang1, Nicholas R Lees1, Seth B Herzon1,2

  • 1Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.

Journal of the American Chemical Society
|February 8, 2021
PubMed
まとめ

この研究は,ルイス酸プロモーターの課題を克服し,塩基性窒素でグリコシドを合成するための新しい方法を導入しています. 新しい還元性リチウム化戦略は,高ステレオ選択性を持つ様々なアミノ糖系を効率的に生成します.

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