Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Anxiety: Overview01:18

Anxiety: Overview

543
Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
543
Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

381
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
381
Panic Disorder01:27

Panic Disorder

340
Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
340
Social Anxiety Disorder01:28

Social Anxiety Disorder

206
Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
206
Anxiolytic Drugs: Overview01:26

Anxiolytic Drugs: Overview

758
Anxiolytic drugs are vital in managing anxiety disorders by effectively alleviating symptoms such as excessive fear, tachycardia, and tremors. There are several classes of anxiolytic medications, each with unique mechanisms of action and potential side effects.
Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic...
758
Anxiolytic Drugs: Benzodiazepines and Buspirone01:29

Anxiolytic Drugs: Benzodiazepines and Buspirone

1.8K
Benzodiazepines are a class of anxiolytic drugs known for their rapid efficacy and high therapeutic-to-lethal dose ratio, but with a potential risk of drug dependence. These drugs are lipophilic, allowing for rapid absorption after oral administration, eventually reaching the central nervous system (CNS). Once in the CNS, benzodiazepines bind to the allosteric site of the GABAA receptor. This binding enhances the inhibitory effects of the neurotransmitter GABA. By doing so, they prevent...
1.8K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Advancing past ketamine: emerging glutamatergic compounds for the treatment of depression.

European archives of psychiatry and clinical neuroscience·2024
Same author

Corrigendum to "Efficacy of a synbiotic in the management of adults with Attention-Deficit and Hyperactivity Disorder and/or Borderline Personality Disorder and high levels of irritability: Results from a multicenter, randomized, placebo-controlled, "basket" trial" [Brain Behav. Immun. 120 (2024) 360-371].

Brain, behavior, and immunity·2024
Same author

Synaptic proteome perturbations after maternal immune activation: Identification of embryonic and adult hippocampal changes.

Brain, behavior, and immunity·2024
Same author

Assessing the Accuracy of Smartwatch-Based Estimation of Maximum Oxygen Uptake Using the Apple Watch Series 7: Validation Study.

JMIR biomedical engineering·2024
Same author

Exploring weight-related self-monitoring as a potential risk factor for eating disorder symptoms in adults - A systematic review and meta-analysis.

Appetite·2024
Same author

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.

medRxiv : the preprint server for health sciences·2024
Same journal

Convergence of metabolic risk in obesity and normal BMI: does risk disappear?

Lancet (London, England)·2026
Same journal

Metabolic traits in obesity and normal BMI in industrialised countries: a multi-country analysis of national population-based studies.

Lancet (London, England)·2026
Same journal

Safety and efficacy of mRNA vaccines: a mechanistic and public health perspective.

Lancet (London, England)·2026
Same journal

The US Ebola response and the future of global health leadership.

Lancet (London, England)·2026
Same journal

Daniel Mason: a tale of change.

Lancet (London, England)·2026
Same journal

The 2026 Wakley-Wu Lien Teh Prize Essay: why medicine, and why stay?

Lancet (London, England)·2026
関連記事をすべて見る

関連する実験動画

Updated: Nov 17, 2025

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat
11:18

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat

Published on: September 12, 2014

15.5K

不安 障害

Brenda Wjh Penninx1, Daniel S Pine2, Emily A Holmes3

  • 1Department of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, Netherlands; GGZ inGeest, Amsterdam, Netherlands.

Lancet (London, England)
|February 14, 2021
PubMed
まとめ
この要約は機械生成です。

不安障害は成人期に発症する一般的な精神疾患で 過剰な恐れや回避が特徴です 有効な治療法がありますが,より良い予防とパーソナライズされた治療法のための研究が進行中です.

さらに関連する動画

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
04:20

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Published on: November 11, 2022

4.9K
Reducing State Anxiety Using Working Memory Maintenance
08:17

Reducing State Anxiety Using Working Memory Maintenance

Published on: July 19, 2017

7.8K

関連する実験動画

Last Updated: Nov 17, 2025

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat
11:18

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat

Published on: September 12, 2014

15.5K
Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
04:20

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Published on: November 11, 2022

4.9K
Reducing State Anxiety Using Working Memory Maintenance
08:17

Reducing State Anxiety Using Working Memory Maintenance

Published on: July 19, 2017

7.8K

科学分野:

  • 精神医学 と 神経科学
  • メンタルヘルスの研究

背景:

  • 不安障害は最も一般的な精神疾患で 通常は成人の初期に発生します
  • 脳の回路の機能不全に関連した 持続的な恐怖や不安や回避行動が特徴です
  • 危険因子には遺伝的,環境的,表遺伝的な影響があり,しばしばうつ病などの併発性疾患があります.

研究 の 目的:

  • 不安障害に関する現在の理解を要約し,その病因,影響,管理について説明します.
  • 併発症や治療抵抗性などの不安障害の治療における課題を強調する.
  • 診断の改善,治療スケーリング,パーソナライズされた医療アプローチの必要性を強調する.

主な方法:

  • 不安障害に関する既存の文献のレビュー
  • 疫学的データと危険因子の分析
  • 現在の治療戦略と研究方向の評価

主要な成果:

  • 不安障害は広範囲に広がり 遺伝や環境の影響が大きいのです
  • 他の疾患との併発は治療を複雑にし,疾患の負担を増加させる.
  • 心理療法 (例えば,CBT) と薬 (例えば,セロトナージック化合物) は有効ですが,予防と抵抗は依然として課題です.

結論:

  • 早期発見と適切な治療は 全世界の不安障害の負担を軽減するために不可欠です
  • 現在の治療法は有効ですが 未だに臨床的ニーズが満たされていないため さらに研究が必要なのです
  • 将来の方向性には,より効果的な不安障害管理のための個別化された精密医療アプローチの開発が含まれます.