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Updated: Nov 16, 2025

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding

Published on: June 9, 2017

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光誘発受容体の閉じ込めは,リガンド独立のGPCRシグナリングを駆動する

M Florencia Sánchez1, Sylvia Els-Heindl2, Annette G Beck-Sickinger2

  • 1Institute of Biochemistry, Biocenter, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.

Science (New York, N.Y.)
|February 26, 2021
PubMed
まとめ

科学者たちは 細胞膜に G タンパク質結合受容体 (GPCR) を 精密に配置する 光制御システムを開発しました この方法はレセプタークラスタを急速に変化させ,リガンド独立のシグナル伝達と細胞応答を明らかにした.

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