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Updated: Nov 12, 2025

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
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アリルニトリルの後期的な炭素同位体交換は,Ni-触媒によるC-CN結合活性化によって行われる

Sean W Reilly1, Yu-Hong Lam2, Sumei Ren1

  • 1Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.

Journal of the American Chemical Society
|March 16, 2021
PubMed
まとめ

この研究では,ニッケル触媒を用いた炭素同位体交換 (CIE) の新しい方法が導入されています. この効率的なプロセスは,薬の開発のための放射性マーケルの化合物の合成を簡素化し,廃棄物を削減します.

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