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D614G置換によるSARS-CoV-2スパイクタンパク質に対する構造的影響

Jun Zhang1,2, Yongfei Cai1,2, Tianshu Xiao1,2

  • 1Division of Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.

Science (New York, N.Y.)
|March 17, 2021
PubMed
まとめ

SARS-CoV-2のスパイクタンパク質のG614型は,ウイルスの拡散と感染性を高めます. 構造分析は,G614のスパイクにおける安定化ループの相互作用を明らかにし,ワクチンの免疫遺伝子の設計を改善しました.

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