関連する実験動画

Updated: Nov 12, 2025

Live Imaging of Nicotine Induced Calcium Signaling and Neurotransmitter Release Along Ventral Hippocampal Axons
12:19

Live Imaging of Nicotine Induced Calcium Signaling and Neurotransmitter Release Along Ventral Hippocampal Axons

Published on: June 24, 2015

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α7ニコチンアセチルコリン受容体の構造とゲート機構

Colleen M Noviello1, Anant Gharpure1, Nuriya Mukhtasimova2

  • 1Department of Neuroscience, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Cell
|March 18, 2021
PubMed
まとめ

アルファ7ニコチンアセチルコリン受容体 (nAChR) の構造的な洞察は,鍵となるゲートメカニズムを明らかにする. Cryo-EM構造は静止状態,活性化状態,無感覚状態を照らし,この重要なイオンチャネルを理解するのに役立ちます.

キーワード:
サイズループ受容体アセチルコリン受容体クリオ・エムイオンチャンネルリガンドゲートイオンチャネルニコチン受容体α7 について

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