関連する実験動画

Updated: Nov 12, 2025

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development

Published on: June 15, 2017

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ガイドラインのNET1とRGMの同時結合は,細胞外NEO1シグナリングをブロックする

Ross A Robinson1, Samuel C Griffiths1, Lieke L van de Haar2

  • 1Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

Cell
|March 19, 2021
PubMed
まとめ

ネオゲニン (NEO1) は,ネトリン-1 (NET1) と反発誘導分子 (RGM) リガンドからの対極信号を統合して三元複合体を形成する. このスーパーアセンブリは 下流の信号を静止し 細胞の成長コーンの崩壊を防ぎ ニューロンの移動を制御します

キーワード:
ネオゲニンネトリンアクソン再生細胞の移動細胞表面受容体複雑な構造モルフォゲン信号タンパク質とタンパク質の相互作用排斥誘導分子信号変換

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