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Updated: Nov 11, 2025

Construction of Model Lipid Membranes Incorporating G-protein Coupled Receptors GPCRs
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Construction of Model Lipid Membranes Incorporating G-protein Coupled Receptors GPCRs

Published on: February 5, 2022

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セロトニン受容体の脂質およびリガンド調節に関する構造的洞察

Peiyu Xu1,2,3, Sijie Huang2,3,4, Huibing Zhang1,5,6,7

  • 1Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Nature
|March 25, 2021
PubMed
まとめ

セロトニン (5-HT) 受容体の構造に関する洞察は,脂質と水分子がそれらの活動をどのように調節するかを明らかにする. この研究は,これらの重要なGタンパク質結合受容体における5HTパナアゴニズムと薬物認識の背後にあるメカニズムを明らかにします.

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