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Updated: Nov 11, 2025

The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
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自発的CXCR6+ CD8 T細胞はNASHで肝臓の免疫病変を引き起こす

Michael Dudek1, Dominik Pfister2, Sainitin Donakonda1,3

  • 1Institute of Molecular Immunology and Experimental Oncology, School of Medicine, Technical University of Munich (TUM), Munich, Germany.

Nature
|March 25, 2021
PubMed
まとめ

非アルコール性脂肪肝炎 (NASH) はT細胞による肝損傷を伴う. 特定のCD8T細胞は代謝の変化により自己攻撃的になり,NASHにおける肝疾患の進行に寄与する.

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