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Updated: Nov 11, 2025

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice
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Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

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ALDH1A3は肺動脈高血圧の遺伝子調節と代謝を調整する

Dan Li1,2,3, Ning-Yi Shao2,4,5, Jan-Renier Moonen1,2,3

  • 1Vera Moulton Wall Center for Pulmonary Vascular Diseases (D.L., J-R.M., S.O., L.W., T.N., E.Y., M.R.), Stanford University School of Medicine, CA.

Circulation
|March 25, 2021
PubMed
まとめ

アルデヒド脱水酵素1A3 (ALDH1A3) は,肺動脈高血圧 (PAH) の滑らかな筋肉細胞増殖のための細胞代謝と遺伝子発現を調整する. PAHの滑らかな筋肉細胞に ALDH1A3を標的とすることは,潜在的な治療戦略を提供します.

キーワード:
細胞サイクルグリコリスメタボリズム筋細胞,滑らかな筋肉拡散肺動脈高血圧

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