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Updated: Nov 10, 2025

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

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NOD2駆動のクローン病における骨髄筋とgp130救済

Shikha Nayar1,2, Joshua K Morrison3, Mamta Giri4

  • 1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Nature
|March 31, 2021
PubMed
まとめ

クローン病ではNOD2の喪失が細胞のバランスを崩し,線維症を引き起こします. この炎症性腸疾患の治療において,gp130を阻害することは有望であり,抗TNF治療の反応を高める可能性があります.

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