Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

4.7K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.7K
Skin Cancer01:30

Skin Cancer

5.1K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.1K
T Cell Types and Functions01:24

T Cell Types and Functions

1.7K
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
1.7K
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

3.2K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
3.2K
EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

3.1K
Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
3.1K
Papillary Dermis01:11

Papillary Dermis

4.7K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
4.7K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Concordance Between Patient- and Physician-Reported Improvement With Dupilumab in Atopic Dermatitis.

The Journal of dermatology·2026
Same author

Lebrikizumab off-therapy remission sustained up to 38 weeks in atopic dermatitis.

The Journal of dermatological treatment·2026
Same author

Advanced Topical Nonsteroidal Therapies for Atopic Dermatitis: Consensus Statements from an Expert Panel.

Journal of drugs in dermatology : JDD·2026
Same author

GLP-1RAs and cardiovascular risk reduction in psoriasis: A retrospective cohort study.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Expert Consensus on Advanced Topical Nonsteroidal Therapies for Chronic Hand Eczema.

Journal of drugs in dermatology : JDD·2026
Same author

Brodalumab's 8-Year Journey in Plaque Psoriasis: Insights into Efficacy, Safety, and Real-World Evidence.

Journal of drugs in dermatology : JDD·2026

関連する実験動画

Updated: Nov 10, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.2K

牛皮病

Christopher E M Griffiths1, April W Armstrong2, Johann E Gudjonsson3

  • 1Dermatology Centre, Salford Royal NHS Foundation Trust, University of Manchester, Manchester, UK; NIHR Manchester Biomedical Research Centre, Manchester, UK.

Lancet (London, England)
|April 4, 2021
PubMed
まとめ
この要約は機械生成です。

牛皮病は遺伝と環境に関係する 慢性的な皮膚疾患です 早期の介入と ライフスタイルの変化は 治療の効果を大幅に減らすことができます

さらに関連する動画

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

597
SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments
06:34

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

Published on: August 8, 2025

288

関連する実験動画

Last Updated: Nov 10, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.2K
Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

597
SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments
06:34

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

Published on: August 8, 2025

288

科学分野:

  • 皮膚科
  • 免疫学
  • 遺伝学

背景:

  • 牛皮病は 世界的に蔓延する 慢性的な皮膚疾患です
  • 併発症には,うつ病,牛皮質関節炎,心代謝症候群が含まれています.
  • 慢性的なプラーク型牛皮病 (牛皮病) は遺伝的傾向 (HLA-C*06:02) と環境要因が関係しています.

研究 の 目的:

  • 牛皮病の病原性を調べるため
  • 現在の治療戦略と新たな治療戦略について議論する.
  • 総合的な患者管理を強調する.

主な方法:

  • 免疫学と遺伝学の研究のレビュー
  • 生物学的薬剤の治療結果の分析
  • 病気管理戦略の検討

主要な成果:

  • インタールイウキン17 (IL-17) とインタールイウキン23 (IL-23) は,牛皮病の主要な要因として特定されています.
  • IL-17,IL-23,Tumor Necrosis Factor-alpha (TNFα) を標的とした生物学的治療は重症の牛皮病の治療に変化をもたらしました.
  • 牛皮病の治療には 個別的なアプローチが必要で 身体的,心理的,それに関連する健康問題も 扱わなければなりません

結論:

  • 牛皮病は複雑で 個人の負担と社会の負担が大きい病気です
  • 現在の治療法,特に生物学的治療法は 深刻な症例の治療に有効です.
  • 早期治療,併発症予防,ライフスタイルの変更に焦点を当てた総合的な管理は,患者の成果を改善するために不可欠です.