関連する実験動画

Updated: Nov 9, 2025

A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells
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A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells

Published on: August 25, 2017

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タイプIII-AのCRISPR免疫は,スタフィロコックの変異を促す

Charlie Y Mo1, Jacob Mathai2, Jakob T Rostøl2

  • 1Laboratory of Bacteriology, The Rockefeller University, New York, NY, USA. cmo@rockefeller.edu.

Nature
|April 8, 2021
PubMed
まとめ

スタフィロコック型III-AのCRISPR-Casシステムは,宿主の変異を増加させることで,細菌の抗生物質耐性を加速します. これは非特異的なDNAの分解によって生じ,微生物の進化に影響を与えます.

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