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Updated: Nov 9, 2025

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures
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腫瘍の微小環境における細胞プログラムされた栄養分離

Bradley I Reinfeld1,2,3, Matthew Z Madden1,4, Melissa M Wolf2,3

  • 1Medical Scientist Training Program, Vanderbilt University, Nashville, TN, USA.

Nature
|April 8, 2021
PubMed
まとめ

免疫細胞と癌細胞は,好ましくは腫瘍の微小環境 (TME) で異なる栄養素を消費する. mTORC1のシグナル伝達によって引き起こされるこの細胞内部の栄養分断は,がん免疫に影響を与え,治療の標的となる可能性があります.

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