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Updated: Nov 9, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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N,N-ダイアルキルヒドロキシラミンとストレインアルキンのバイオオートゴナル・レトロコップ除去反応

Dahye Kang1,2, Justin Kim1,2

  • 1Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.

Journal of the American Chemical Society
|April 8, 2021
PubMed
まとめ

N,N-ダイアルキルヒドロキシラミンとサイクロオクチンを用いた新しいバイオオートホーゴン反応は,高度に地域選択的変換を提供します. この安定で化学選択的なレトロコップ除去反応は,生物結合化学のツールキットを拡張します.

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